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Wu Da's latest coronavirus research: Women's incubation period is longer, isolation should exceed 14 days

Hits: 3890019 2020-03-08

The team's review of the literature on the relationship between patient admission time and sex ratio suggests that the proportion of newly diagnosed males decreases as the duration of the outbreak increases. The team further analyzed 2045 cases (953 males and 1092 females) confirmed in the hospital as of February 20 this year. Among them, there were 454 cases (47.6%) in mild to moderate group, 612 cases (56.0%) in female group, 387 cases (40.6%) in severe group, 404 cases (37.0%) in female group, 112 cases (11.8%) in severe group, 76 cases (7.0%) in female group.
In addition, the researchers found 67 asymptomatic infections, 47 of which were female. This shows that women account for a large proportion not only in mild to moderate patients, but also in asymptomatic infections. Data show that more men than women were admitted before January 20, but since then more women than men. Both the literature and the hospital's data show that the proportion of women admitted to hospital in the early stage of the epidemic is relatively low, but in the late stage of the epidemic, the proportion has increased.
These data may indicate that women not only have relatively mild symptoms, but also have a longer incubation period than men, perhaps because women are born with stronger antiviral immunity than men. The fact that women are not diagnosed does not mean that they are not infected, but that their symptoms are mild or asymptomatic. The common explanation is that the interaction between sex hormones and the immune system makes men more vulnerable to pathogens than women. In general, women tend to have a stronger immune response, which helps them to eliminate infection more quickly and reduce the risk of disease progression. But as long as there is virus infection, the virus will constantly fight against the human immune system. Before the virus breaks through the immune system, the human body has no symptoms of any disease, which is the incubation period. "You have a longer incubation period when your immune system is able to withstand the virus for a longer period of time, but not kill it completely." The authors wrote. The asymptomatic onset and long-term incubation period of women will undoubtedly have an important impact on the spread of the new coronavirus. For example, infected women will be asymptomatic and in contact with others, even after the end of active or passive isolation, they may still "escape" the diagnosis and cause subsequent virus transmission. A recently reported case with a long incubation period and a high transmission rate is also a female case. To sum up, the author believes that the number of men and women who eventually infect covid-19 should be about the same. As time goes on, more female patients with long incubation period are diagnosed, and the proportion of female patients increases gradually. However, it is worth noting that studies have shown that the symptoms of infected men are much more serious than those of women, which may be attributed to the innate strong antiviral immunity of women. According to the results of this study, the research team calls on China and other countries or regions in the world to take differentiated disease control measures for women as soon as possible. For example, during the screening process, women with a clear contact history should be tested for nucleic acid directly, and the isolation period of women under medical observation should also exceed 14 days, regardless of symptoms. We call on China and the rest of the world to adopt different control measures for women as soon as possible "Maybe this will speed up the end of the epidemic and reduce the cost of controlling it."
Source: global network, surging news
Edited by: Aboriginal brother

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