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Strong substitute: medicinal soap is again favored

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Strong substitute: medicinal soap is again favored

Soap is an essential washing and care product in daily life. It uses sodium fatty acid and other surfactants as its main raw materials, and adds quality improvers and appearance improvers. After processing, it is still used by many families. After the outbreak, "Shanghai medicinal soap" has also become a snapping target for people. During the SARS period in 2003, the "Shanghai medicinal soap" of the Shanghai Soap Company made important contributions to the fight against SARS. The products such as Shanghai sulfur soap, Shanghai medicinal soap, and medicated soap hand sanitizer have also been reported by the Shanghai Emergency Commodity Library every month.

It is understood that Shanghai medicinal soap started in 1959 and is China's first special-purpose sterilizing soap. It has been improved and has been selling well for a long time. Soap contains a small amount of phenol, which can kill Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, hemolytic streptococcus and hepatitis bacteria. For nearly half a century, its unique formula and washing effect have been favored by generations. Facing this war without gunpowder smoke, on January 30, Shanghai Soap-Making Co., Ltd. was approved by the Municipal Economic and Information Commission to resume work in advance, and some production capacity was resumed the next day. From February 2nd, the production of medicinal soap, hand sanitizer and disinfectant was resumed and delivered to customers one after another. The company stated that in the future, it will go to full force to do a good job in the allocation of raw materials and personnel, and go all out to ensure that Shanghai public safety kills products. Market supply.

Bactericidal component: p-chloroxylenol

General hand sanitizer formulations have decontamination, care, antibacterial, sensory adjustment, and natural ingredients, of which the first three have chemical ingredients.

Detergent ingredients are mainly anionic surfactants, as well as a small amount of non-ionic, zwitterionic surfactants, designed to provide detergency and rich foam. Commonly used anionic surfactants are soap, sodium lauryl sulfate, Q-olefin sulfonate, fatty alcohol polyoxyethylene ether sulfate, Q-sulfo fatty acid ester, lauroyl sarcosinate, and monooleic acid amide Disodium sulfosuccinate and so on. Non-ionic surfactants are rarely used in hand sanitizers. A small amount of it can improve the detergency effect and improve the stability of the foam, such as cocoic acid diethanolamide. The addition of alkyl glycosides can reduce the effect of surfactants on the skin. stimulate. The addition of a small amount of zwitterions is beneficial to the foaming and long-lasting foam, such as betaine and amine oxide.

Due to the degreasing effect of surfactants, the skin feels dry after washing hands. Therefore, some fat rich agents and emollients should be added to replenish skin oil to prevent dry and rough skin, such as various natural and synthetic lanolin, glycerin, propylene glycol, sorbus Alcohols, lactates and sodium pyrrolidone carboxylates.

The hand is always in contact with the outside world, and it will inevitably be contaminated with various bacteria and even fungi. Therefore, the bactericidal component must have a broad spectrum. The more common bactericidal ingredient in hand sanitizer is mainly p-chloroxylenol, which is a low-toxic, broad-spectrum phenol disinfectant, which has a killing effect on most Gram-positive and negative bacteria, fungi, and molds. It can be widely used as antifungal and antibacterial agent in disinfection or personal care products.

Under normal conditions, p-chloroxylenol is a white to off-white crystalline powder with a weak odor of phenol. Its solubility in water is 0.03%. It is easily soluble in organic solvents such as alcohol, ether, polyglycol and strong alkaline aqueous solution. Besides being used as a disinfectant, it can also be used as a preservative and antifungal agent. It is safe for human body and the environment.

The concentration of p-chloro-xylenol in different hand sanitizers ranged from 0.1% to 0.4%. In theory, the higher the concentration, the better the sterilization effect, but too high a concentration can easily cause problems such as dry skin and cracking of the hand. Experts point out that the germicidal effect of hand sanitizer also depends on the overall formula of the ingredients. The formula is well formulated, and low concentration can achieve better sterilization effect; if the formula is not good, high concentration does not necessarily achieve good results. This is because the compounds in the hand sanitizer interfere with each other, so the formula is also important to measure the bactericidal effect.

It should be noted that the special hand sanitizer for hospitals is different from the domestic hand sanitizer. The hand sanitizer disinfection products used by doctors under specific conditions such as pre-operation and blood draw are basically free of anionic surfactants. They are mainly composed of double-chain quaternary ammonium salts, chlorhexidine acetate, and gluconate chlorhexidine , Diclofenac hexane gluconate, benzalkonium chloride, ethanol, isopropanol, polyhexamethylene biguanide and auxiliary.

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